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BPSL0498 BPSL0498 ptsH ptsH BPSL0440 BPSL0440 BPSL0499 BPSL0499 BPSS1150 BPSS1150 BPSS1957 BPSS1957 BPSL0500 BPSL0500 BPSL0322 BPSL0322 BPSL0531 BPSL0531 glpK glpK BPSL1304 BPSL1304
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BPSL0498Similar to Pseudomonas aeruginosa probable phosphotransferase protein pa3760 SWALL:Q9HXN5 (EMBL:AE004794) (842 aa) fasta scores: E(): 8e-102, 49.53% id in 860 aa. C-terminus is similar to the C-terminal region of Rhodobacter capsulatus multiphosphoryl transfer protein frub(hi) SWALL:PTF1_RHOCA (SWALL:P23388) (827 aa) fasta scores: E(): 2.7e-78, 40.73% id in 739 aa; Belongs to the PEP-utilizing enzyme family. (872 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr; Similar to Escherichia coli Salmonella typhimurium, and Salmonella typhi phosphocarrier protein HPr or PtsH SWALL:PTHP_ECOLI (SWALL:P07006) (85 aa) fasta scores: E(): 3.2e-08, 40.96% id in 83 aa, and to Alcaligenes eutrophus phosphocarrier protein hpr phbH SWALL:PTHP_ALCEU (SWALL:P23537) (89 aa) fasta scores: E(): 2.8e-26, 79.77% id in 89 aa.
 
 0.999
BPSL0440
Putative phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
0.999
BPSL0499
Phosphotransferase system, IIbc component; N-terminus is similar to the N-terminal region of Escherichia coli PTS system, N-acetylglucosamine-specific IIabc component NagE or PstN SWALL:PTAA_ECOLI (SWALL:P09323) (648 aa) fasta scores: E(): 1.2e-88, 52.51% id in 516 aa. Full length CDS is similar to Pseudomonas aeruginosa probable phosphotransferase system protein pa3761 SWALL:Q9HXN4 (EMBL:AE004794) (570 aa) fasta scores: E(): 1.2e-85, 56.15% id in 577 aa.
 
 0.999
BPSS1150
Similar to Alcaligenes eutrophus phosphocarrier protein Hpr phbH SWALL:PTHP_ALCEU (SWALL:P23537) (89 aa) fasta scores: E(): 4.2e-05, 39.13% id in 69 aa, and to Ralstonia solanacearum probable phosphocarrier protein Hpr PstH or rsc0347 or rs03314 SWALL:Q8Y2I9 (EMBL:AL646058) (89 aa) fasta scores: E(): 9.4e-05, 38.37% id in 86 aa.
 
 0.999
BPSS1957
Similar to Escherichia coli 6-phosphofructokinase isozyme 2 PfkB or b1723 SWALL:K6P2_ECOLI (SWALL:P06999) (309 aa) fasta scores: E(): 1.8e-31, 39.48% id in 309 aa, and to Salmonella typhimurium 6-phosphofructokinase II Pfkb or stm1326 SWALL:Q8ZPT5 (EMBL:AE008757) (310 aa) fasta scores: E(): 7e-32, 39.15% id in 309 aa; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.980
BPSL0500
Putative chitobiase; Similar to Serratia marcescens chitobiase precursor Chb SWALL:CHB_SERMA (SWALL:Q54468) (885 aa) fasta scores: E(): 2e-118, 46.94% id in 801 aa, and to Burkholderia cepacia putative chitinase Bcc1 SWALL:Q9F1K5 (EMBL:AB053088) (826 aa) fasta scores: E(): 0, 85.8% id in 831 aa. CDS is truncated at the C-terminus in comparison to orthologues.
  
  
 0.913
BPSL0322
LacI family regulatory protein; Similar to Bacillus subtilis degradation activator DegA SWALL:DEGA_BACSU (SWALL:P37947) (337 aa) fasta scores: E(): 5.3e-19, 30.29% id in 340 aa, and to Xanthomonas campestris transcriptional regulator xcc3356 SWALL:Q8P5I5 (EMBL:AE012454) (343 aa) fasta scores: E(): 2.8e-24, 37.72% id in 334 aa.
 
 
 
 0.904
BPSL0531
Similar to Escherichia coli nitrogen regulatory IIA protein PtsN or RpoP SWALL:PTSN_ECOLI (SWALL:P31222) (163 aa) fasta scores: E(): 1.9e-13, 36.3% id in 146 aa, and to Ralstonia solanacearum putative nitrogen regulatory IIA rsc0406 or rs03374 SWALL:Q8Y2D0 (EMBL:AL646059) (151 aa) fasta scores: E(): 2.6e-44, 78.14% id in 151 aa.
 
  
 0.901
glpK
Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 
 0.897
BPSL1304
Putative LacI-family transcriptional regulator; Similar to Escherichia coli, and Escherichia coli O157:H7 ribose operon repressor RbsR or b3753 or z5254 or ecs4695 SWALL:RBSR_ECOLI (SWALL:P25551) (329 aa) fasta scores: E(): 6.4e-26, 33.64% id in 321 aa, and to Ralstonia solanacearum probable transcription regulator protein rsc1790 or rs04189 SWALL:Q8XYG8 (EMBL:AL646066) (360 aa) fasta scores: E(): 2.4e-62, 56.39% id in 344 aa.
 
 
 
 0.897
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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